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Copper induces cell death by targeting lipoylated TCA cycle proteins

A recent investigation has shown that more than 3000 proteins are constitutively S-nitrosated, which are involved in cell signaling and regulation of tissue homeostasis [26,28]

This is of particular interest for conditions like Alzheimers or Parkinsons disease

This THF derivative is required for the synthesis of thymidine which is catalyzed by thymidylate synthetase
