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It is common that not enough vitamin B12 is ingested or not enough of the vitamin is absorbed despite eating foods containing this vital vitamin

Clinical studies suggest collagen supplementation may help: reduce knee osteoarthritis pain improve joint function support tendon rehabilitation when combined with exercise Examples of Osteoarthritis studies: Examples of Tendon studies: Unlike injectable peptides, collagen supplements function as nutritional support, not pharmacologic signaling molecules

Tolerance develops

Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning