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In Denmark, however, patients receive injections of 1 mg cyanocobalamin per week during the first month and every 3 months after that, or 1 mg hydroxycobalamin every other month.

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Plasma vitamin B 12 and plasma folate concentrations will be estimated by microbiological assays using a chloramphenicol-resistant strain of Lactobacillus casei and colistin sulfate-resistant strain of Lactobacillus leichmannii , respectively