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Focal relationship between structure and function within the central 10 degrees in glaucoma

Nature (2020) 583(7817):596602

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Comprehensive studies on the excitation state, fluorescence spectrum and maximal intensity of curcumin in different solvents, micro-heterogeneous systems and bio-mimetic systems showed high sensitivity and dependency towards the nature of solvents [63, 68, 69]

A central mechanism driving such pathological scarring is the persistent activation of the transforming growth factor-beta (TGF- )/Smad signaling pathway, which continuously stimulates fibroblasts and myofibroblasts, resulting in excessive collagen deposition and fibrotic remodeling (31, 32)