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Precision modeling of mitochondrial disease in rats via DdCBE-mediated mtDNA editing

doi: 10.3389/fendo.2026.1781679 Received 06 January 2026 Revised 16 February 2026 Accepted 19 February 2026 Published 11 March 2026 Volume 17 - 2026 Edited by Alpo Juhani Vuorio, University of Helsinki, Finland Reviewed by Diana Rodrguez Vera, Instituto Politecnico Nacional, Mexico Nana Afia Ntim, University of Ghana, Ghana Updates Copyright 2026 Zhu, Qu, Li, Deng, Shen and Chen

Physiological and metabolic consequences of aging Aging is associated with numerous physiological changes all over different organ system due to their reduced capacity and deterioration

Oral administration allows the peptide to come into direct contact with the gut lining, making it a logical choice for conditions such as: The trade-off with oral BPC-157 is that it must survive the acidic environment of the stomach and the enzymatic activity of the digestive tract