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Description
There is increasing interest in developing tripeptides with targeted therapeutic functions, particularly for applications in wound healing 36 , 75 , 92 , as well as in cancer 60 , 170 , neurodegenerative 24 , 173 , and cardiovascular diseases 177 , 178 , and in the design of functional foods 179 , 182 , 188

In this review, we summarize the most recent advances on INDDs, including widely studied liposomes, LNPs, polymeric nanoparticles, protein and peptidebased nanoparticles, mesoporous silica nanoparticles, extracellular vesicles, and cell membranederived nanovesicles, focusing on design strategies for enhancing mucus and surfactant penetration, targeting specific lung lesions and cells, and stability during inhalation and storage
This peptide is valuable for those looking to replace MOTS-c with an alternative that offers rejuvenating effects on energy levels and metabolic efficiency

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