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A deep understanding of the molecular mechanisms that regulate the expression and function of carnitine transporters opens new prospects for the treatment of a variety of diseases
In summary, the acetyl-L-carnitine group scored better when assessing patient function using the modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) score, and supplementation caused a significant decline in the serum levels of TNF- , ICAM-1, IL-6, and NSE and a significant increase in the serum level of superoxide dismutase (SOD), TAC, GPx, and total L-carnitine in the subjects with acute ischemic stroke compared to the placebo treatment
Perhaps most impressively, L-carnitine has been linked to a reduction in cardiovascular-related deaths
CoQ10 supports normal mitochondrial function and normal antioxidant defense
