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doi: 10.1016/j.cell.2016.11.035

Nat Rev Clin Oncol (2022) 19(5):34255

2.3 Mitochondrial dysfunction Mitochondria, with their functions in energy production, calcium homeostasis, and membrane excitability, are thought to substantially impact the pathology of IBD, as their dysfunction may initiate and advance the disease

Understanding the metabolic mechanisms of drug candidates using metabolic models greatly aids in the development of drug delivery systems with optimal properties

Oral fluid has similar characteristics: is a convenient, non-invasive method for screening but it is not a reliable method to assess recent use within the impairment window (Gregorio et al., 2024)
