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The second role of TB500, which is sometimes referred to as moonlighting, is to regulate inflammation through changes in gene expression patterns rather than via actin sequestration

[DOI] [PubMed] [Google Scholar] Bernardo VS (2021) Ergotionein as a therapeutic alternative: antioxidant and/or modulating effects on K562 erythroleukemic cells [Master thesis, Universidade Estadual Paulista]

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Excess amino acids, both from protein degradation in the absence protein synthesis a disruption of the balnace between protein synthesis and protein degradation and dietary input are degraded, resulting in an increase in ammonia and ammonium ion, which are converted to urea for disposal