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And it is after RBD binding to the host cell receptor (ACE2) that the sequential cleavage of S-protein at the S1/S2 and S2 cleavage sites causes an irreversible conformational change in the S2 subunit, which subsequently initiates membrane fusion with the host cell
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ScRNA-seq and TCR sequencing analyses revealed that ECM viscoelastic properties directly modulate T cell phenotypes [143]
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