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Previous attempts to overcome these problems have either been unsuccessful and/or not feasible

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After surgery, patients received atezolizumab (a PD-L1 antibody), cevumeran and mFOLFIRINOX (a four-agent chemotherapy) in sequence

The testes require a precise balance of reactive oxygen species and antioxidants, and excessive homocysteine disrupts this balance, leading to oxidative stress [65], and subsequently impairs synthesis of testosterone
