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As a consequence, D2KO mice are deaf underlining the importance of D2 in producing local T3 in the cochlea during a critical period of its development (101)
Emerging roles of xanthine oxidoreductase in chronic kidney disease

In line with its mitoprotective nature, mitoQ-treated rats subjected to prolonged TAC also displayed preserved mitochondrial membrane potential and respiratory chain function as well as reduced sensitivity to oxidant-induced MPTP 99
The authors concluded that GHK acts by affecting TGF-1/Smad 2/3 and IGF-1 pathway