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It is noteworthy that an excessive dietary intake of methionine-rich animal protein is an additional cause of hyperhomocysteinemia detected both in the fasting state and after an oral methionine load, especially when tissue folate and cobalamin stores are intact

347,348 Notably, miRNA-mediated gene expression control is critical for the cellular response to the environmental stresses, like starvation, hypoxia, oxidative stress, and DNA damage

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Nature 509 , 492496 (2014)