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Description
If the sample contains pathological alpha-synuclein, it induces templating, misfolding and aggregation of the monomers, resulting in a high -pleated sheet content of the protein, which binds ThT, resulting in increased fluorescence after several hours
For this reason, 4MSP and its precursors were not further investigated in this study
doi: 10.21037/atm-2019-cm-08
Eur J Pharmacol 854:224231
Itaconate: A promising precursor for treatment of neuroinflammation associated depression
