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Considering Patnaiks criteria for grade 3 tumors, when evaluating proliferative indices, some cases with low mitotic indices that present with aggressive behavior are excluded or underestimated [73,79,80,87,88,89]

Cathodal iontophoresis increased drug permeation threefold, while combining both approaches resulted in a four-fold enhancement in Gap junction protein connexin43 (Cx43) specific antisense oligodeoxynucleotide permeation
2025;86: e70044

Another important direction is the identification of bioavailability-enhancing strategies specific to TCM

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