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Description
ALDH2 variants with Cys301, Cys303 and Glu268 singly, doubly or triply mutated exhibit significant loss of GTN denitrating activity, 9 indicating that all three residues are somehow involved in catalyzing NO 2 release from GTN

Most known selenoproteins, such as glutathione peroxidase, are expressed in the thyroid and are involved in thyroid hormone metabolism, redox state regulation, and maintenance of cellular homeostasis

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