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Description
Glutathion ist einer der strksten intrazellulren (innerhalb der Zelle) Abwehrnhrstoffe, der in fast jeder Krperzelle vorkommt und besonders in den Zellen, die am anflligsten fr Toxizitt sind, wie Gehirn, Nieren, Leber, Herz, Lunge, Haut, Darmepithel, Hornhaut und Netzhaut, hochaktiv ist 2

Besides xCT/GPX4 inhibition (by Erastin/Sulfasalazine/RSL3), 379,380,381 FSP1 inhibitors (iFSP1, Liproxstatin-1) and DHODH blockers (TPP-brequinar/B2, Leflunomide) disrupt organelle membranes and mitochondrial antioxidants, respectively

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Emerging epigenetic evidencederived predominantly from experimental animal modelssuggests that prolonged or repeated exposure to supraphysiological doses of anabolicandrogenic steroids may induce persistent molecular alterations in the male reproductive system
