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Moreover, it was postulated that the aromatic ring of the 3-homotyrosine side chain and the C-terminal phenyl ring interact and Phe550 in IRAP further stabilizes aromatic/hydrophobic packing ( More recently, a crystal structure of IRAP with the macrocyclic peptide inhibitor 23 (HA08) was reported (Mpakali et al., 2020)

10.1038/s43587-024-00607-1 245 WuY.ZhouS.ZhaoA.MiY.ZhangC

Glutathione antioxidant system and methylmercury-induced neurotoxicity: an intriguing interplay

PMID: 161 TurrellFKOrhaRGuppyNJGillespieAGuelbertMStarlingCet al