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Description

Metabolic changes in synovial cells in early inflammation: involvement of CREB phosphorylation in the anti-inflammatory effect of 2-deoxyglucose

Meanwhile, although muco-penetrating particles penetrate mucus more effectively than mucoadhesive particles, they may experience back diffusion owing to concentration gradients 206

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Important considerations include effective delivery methods, metabolic stability, dose-response relationships, and the potential for off-target effects when manipulating growth-factor signaling