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The treatment was well tolerated and highly efficacious, possibly improving hepatic histology and suppressing NASH through the inhibition of NF-B, mitigating renal disease, and improving metabolic disturbances [226]
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Taken together, the data indicate that colistin-induced mitochondrial depolarization occurs upon the opening of the mPTP
As of 7 June 2023, an estimated 767,750,853 confirmed cases of COVID-19 have occurred, which have resulted in 6,941,095 deaths [1]
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