glutathione and bowel movements Liposomal An Open-Label Case Series of

Trx1 is showing good efficacy with no major side effects (unpublished data)

Chemical activation of Nrf2 by pretreatment with tBHQ increases the survival of neuroblastoma cell in response to three chemotherapeutic drugs, namely cisplatin, doxorubicin, and etoposide.12 Drug resistance toward tamoxifen in MCF7 cell lines driven by Nrf2 activation is attributed to antioxidant enzymes, including Trx, Prx, and GCL.11 Several phase II enzymes regulated by Nrf2 have also proved to be chemoresistance

In addition, melatonin treatment has also been shown to inhibit the production of pro-inflammatory cytokines through the NF-B pathway (Tiong, Ng, Koh, Ponnudurai, & Chye, 2019

Often yes, with sensible timing

The practical questions researchers ask are always the same: how much per day, and by what route