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Epigenetic Impact: The Methyl Sink Phenomenon 4.1 Global Hypomethylation NNMT depletes cellular SAM pools, reducing methyl availability for DNA and histone methyltransferases , leading to global hypomethylation in many contexts

[DOI] [PubMed] [Google Scholar] 225.Chen F., Marquez H., Kim Y.-K., Qian J., Shao F., Fine A., Cruikshank W.W., Quadro L., Cardoso W.V

Danger if you dont take your B12 but following a plant-[based] diet during pregnancy may be protective against the development of preeclampsia, pre-gravid obesity, and minimize the exposure to [DNA-damaging] agents. It may also protect our newborns from the onset of pediatric diseases, such as pediatric wheezing, diabetes, neural tube defects, orofacial clefts, and some pediatric tumors. Vegan pregnant women have a lower-than-average rate of cesarean section, less postpartum depression, and lower neonatal and maternal mortality, with no complications or negative outcomes that are higher than average. In addition, a lower incidence of what used to be called toxemia, a potentially dangerous pregnancy complication known as preeclampsia

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Resynthesis of the essential amino acid methionine in the body is mediated by Vitamin B12