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Xue-Chun Hu, [email protected] These authors have contributed equally to this work This article was submitted to Reproduction, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In summary, the three antioxidant systems Xc -GSH-GPX4, FSP1-CoQ 10 -NAD(P)H, and GCH1-BH 4 can scavenge lipid peroxides during ferroptosis

It contains Alpha Lipoic Acid, Vitamin C and L-Glutathione as main ingredients that helps to replenish the nutrients deficiency and has a wide antioxidant property that provides nourishment to the body

Thus, further studies must be conducted in the future to address these challenges

U.JorissenM.AugustijnsP.SciotR.VerbekeN.et al (2000)