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Chemotherapy-caused DNA damage activates a series of DNA damage response (DDR), including the activation of ATM/ATR, and then triggers the downstream cell processes, such as cell cycle arrest, DNA damage repair, cell senescence or apoptosis [5]

It involves progressive cognitive decline, fluctuating attention levels, visual hallucinations, REM sleep behavior disorder, and Parkinsonism

Therefore, CHE can be used as one of the main representatives of the anticancer effect of these four traditional plants, combined with the needs of contemporary cancer drugs

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Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene