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The findings identify a robust pathway to hepatic maturation, with Day 30 emerging as the developmental peak characterized by optimal drug-metabolizing enzyme expression and functional hepatic features

*Correspondence: Azhar Hussain [email protected] Wang [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Nutrition and Food Science Technology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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