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3 However, at pharmacological doses, GIP agonism appears to increase fat oxidation by promoting futile calcium cycling, thereby diminishing the metabolic adaptation often observed with weight loss

Tesamorelin handles GH-driven fat metabolism, specifically the reduction of visceral abdominal fat

Khafagy el et al., 2009a

The absence of reported adverse events in small, uncontrolled studies from a single lab is not the same as established safety
