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Besides a high expression, also a high activity of Pgp determines doxorubicin resistance

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TC and LDL-C concentration is reduced for several weeks after a cardiovascular event and in chronic inflammation, e.g., in rheumatic diseases (lipid paradox), as well as in the elderly, especially those over 75 years of age [4, 56, 57]

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It is possible that in D55 heart, LPL derived FA are directed towards oxidative metabolism rather than storage (Figure 2) [94]

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