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Dendritic Cells The PLGA microparticles induce tolerogenic dendritic cells (tDCs), promoting regulatory T cell (Treg) expansion and reducing arthritis symptoms

doi:10.1038/s41394-018-0100-9 19

S., & Srivastava, A

In previously published protocols different types of derivatization reagents (CMQT or CMLT), different pH of the buffer used in the protocols (7.4) and shorter time of sample reduction and derivatization (3 min) were applied (Tables 3 and 4.) Changing the conditions of reduction and derivatization increases the efficiency of this process, which may give higher final concentrations of the analytes

And then there's Vitamin C