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Some neurological effects improve with sustained abstinence

The same authors also demonstrated that MPP+ induced ferroptosis in Lund human mesencephalic (LUHMES) cells, which are immortalized dopaminergic neuronal precursor cells that can differentiate into dopaminergic neurons (Zhang et al., 2014)

Hartong DT, Berson EL, Dryja TP

Many drugs contain functional groups that can act as nucleophiles or electrophiles, influencing their reactivity in the body

[PMID: 11028671 DOI: 10.1034/j.1399-3003.2000.016003534.x] [DOI] [PubMed] [Google Scholar] 53.Roum JH, Borok Z, McElvaney NG, Grimes GJ, Bokser AD, Buhl R, Crystal RG