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Therefore, the generation of these NF1 minipigs paved a path for the field to interrogate NF1-related molecular pathogenesis, explore therapeutic options, and conduct preclinical testing in large animal models that hopefully present closer resemblance to human patients

Similarly, lung congestion appears as a common outcome (i.e., time-dependent and time-independent features that can be acute respiratory distress syndrome exudative phase features) [29,30]

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2016;84(3):177.e1177 e8