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For targeted pigmentation, laser therapy or chemical peels may offer faster results, while topical treatments and oral antioxidants provide gradual improvement

Novel oxicam analogs, particularly those with an arylpiperazine moiety at the thiazine ring, have shown greater efficacy in downregulating DDAHs and PRMTs and upregulating ARG2 compared to traditional oxicams such as piroxicam and meloxicam (157, 158)

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