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doi:10.1073/pnas.37.11.729

, compromised blood brain barrier resulting in increased permeability, increased activation of microglia and astrocytes producing pro-inflammatory cytokines, and damaged myelin/white matter tracks [9], [24][36])
10.1109/TNNLS.2024.3424784 375 WangJ.ShaoF.YuQ

The delivery route matters enormously, and the human evidence base for either route is far thinner than the online discussion suggests

Jonsson R, Brokstad K, Jonsson M, Delaleu N, Skarstein K, Current concepts on Sjogrens syndrome classification criteria and biomarkers, 2018 Oct: 126(Suppl 1): 37-48
