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The specific mechanism of the protein sparing effect of L-carnitine is detailed in Fig
Brain acylcarnitines can function in synthesizing lipids, altering and stabilizing membrane composition, modulating genes and proteins, improving mitochondrial function, increasing antioxidant activity, and enhancing cholinergic neurotransmission. 9 Currently a relatively small subset of acylcarnitines is usually investigated
Blood analysis for L-carnitine derivatives showed that glutaryl carnitine and carnosyl carnitine were significantly decreased in ASD group and the authors of this publication suggested that those 2 compounds may be potential biomarkers for diagnosis of ASD
However, the precise AR domain(s) that are most relevant for this phase separation is still being debated [98, 101, 102]
[15] Acetyl-CoA coenzyme A
