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NRG-GI008: Colon adjuvant chemotherapy based on evaluation of residual disease (CIRCULATE-NORTH AMERICA)

90 However, ME1 and ME2 seem to be the main isoforms because ME3 is hardly negligibly detected in many assessed mammalian cells

Lancet (2004) 364(9443):141120

Increasing studies have confirmed that obesity, metabolic status and gut microbiota imbalance can promote the occurrence of OA through the metabolism-inflammation-oxidative stress network, which is closely related to daily nutrition or dietary intake

Succinate, the conjugate base of succinic acid, is a metabolic intermediate in the TCA cycle, and a metabolic signaling molecule in inflammation processes [71]
