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Furthermore, whereas administration of either [ 35 S]-Met or [ 35 S]-cystine resulted in rapid [ 35 S]-labeling of hepatic GSH and protein pools in control mice, only administration of [ 35 S]-Met, not [ 35 S]-cystine, appreciably radiolabeled either hepatic GSH or protein pools in mice with TrxR1/Gsr-null livers [107]

It is indicated to reduce serum phosphorus in adults with chronic kidney disease (CKD) on dialysis who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy