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Linkermann et al., 2014)
Role of peroxisomes in ros/rns-metabolism: implications for human disease

Heme Oxygenase-1 (HO-1) plays a crucial role in the antioxidant system by converting heme into biliverdin, which is then reduced to bilirubin, a potent antioxidant (Clark et al., 2000)

447 In multiple trials, ICIs and chemotherapy could exert synergistic effects

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