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Panganamala RV, Karpen CW, and Merola AJ (1986)

Curcumin and omega-3 ameliorate experimental osteoarthritis progression in terms of joint pain and mitochondrial dysfunctionJournal of Inflammation | July 2025Curcumin, extracted from Curcuma species and commonly referred to as turmeric, is a medicinal ingredient and spice used in Asia with proven stability, exhibiting antioxidant and anti-inflammatory properties that make it a valuable therapeutic agent for osteoarthritis, a chronic degenerative disorder causing joint pain and cartilage destruction

doi: 10.3390/nu17152537 25 ChenQ.FanY.ZhangB.YanC.ZhangQ.KeY.et al

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Taken together, human in vitro and in vivo studies suggest that CYP3A4 plays a minor role in the bioactivation of low dose APAP