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While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function

doi: 10.1016/j.biopha.2005.06.014

The reference list and citation index of each screened article were checked for their impactful utility, and only the articles that possessed potentially relevant citations were included in the study

Spatial discrimination learning and choline acetyltransferase activity in streptozotocin-treated rats: effects of chronic treatment with acetyl-L-carnitine Brain Res 1995

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