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An additional chromatin study in synovial fibroblasts reveal histone-methylation/STAT3 crosstalk controlling IL-6-driven effector genes, underscoring how methyl-donor availability and chromatin state co-regulate cytokine programs (122)

Scheurich, and H

Although it has been shown that different myelin lipids directly activate the TREM2 pathway (139), the hypothesis of a transition from MIMS-foam to MIMS-iron after myelin phagocytosis has not yet been investigated, but it is possible that these signatures correspond to different phases of activation from the same cell