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Kelm, M., Preik-Steinhoff, H., Preik, M

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8 The geographic overlap between regions with documented high PA exposure and elevated PAH burden observed in our findings suggests this pathway may contribute to the unexplained hemolytic disorders driving global PAH incidence, although this hypothesis requires verification through direct biomarker studies, such as measurement of blood pyrroleprotein adducts or urinary PA metabolites in high-risk populations