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6.1.2 Membrane damage Mitochondrial membranes, due to their lipid-rich composition, are highly vulnerable to ROS attack in diabetic cardiomyopathy, which in turn enhances the toxicity of 4-HNE

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J Infect Dis (1996) 173(3):7358

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This mechanism is plausible biochemically, and some human trials support it but with important limitations

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It is a naturally occurring nonapeptide a chain of nine amino acids first identified in rabbit brain tissue in the 1970s

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