b12 injections side effect injection effects : r/B12_Deficiency What are the benefits of

Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM

Common Neurobion Forte Injection side effects are: Injection site pain Redness or swelling Nausea Headache Dizziness Stomach discomfort Skin rash or itching These effects are usually temporary and do not require medical attention

One study investigating these effects in obese mice discovered that administration of an NNMT blocker reduced insulin serum levels by 50-60% in the subjects

However, its important to note that B12 shots are most beneficial for those who are truly deficient

Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program