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Podocyte-specific MDM2-knockout mice develop TP53-mediated kidney injury through the activation of a mixed type of cell death, including ferroptosis

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Liu J, Xu C, Chen L, Xu P, Xiong H

Therefore, ascorbate can protect against glutamate-induced excitotoxicity and neurodegeneration

873 The expression of ACSL4 and 4-HNE increase in the cartilage of OA patients and OA mice, while metformin increases p-AMPK and p-ACC levels in IL-1-treated chondrocytes, reverses ACSL4 and 4-HNE positive chondrocytes and OA lesions, and improves the ferroptosis sensitivity of chondrocytes through the AMPK/ACC pathway