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Neurospectroscopic alterations have been reported with increase in the Glx/creatine (Cr) ratio accompanied by decrease in myo-inositol (mI)/Cr ratio and total choline (tCho)/Cr ratio in liver disease (30,46,47)
4 and Supplementary Table 13)
All animal experiments were performed according to protocols approved by the Animal Care Committee of Shandong University (No
ERS can activate the expression of Ca 2+ release channels on inositol 1,4,5-trisphosphate receptors (IP3R), thereby mediating the release of ER-Ca 2+
PMID 19321896
