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Hypoxia induces amino acid import in PIK3CA -MT, but not PIK3CA -WT, SW48 colorectal cancer cells Guided by the analysis of public gene expression profiles across various cell lines, which suggested a potential involvement of aspirin in amino acid metabolism and hypoxic signaling particularly in HT-29 cells, we sought to examine whether these associations were linked to PIK3CA mutation status

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Statistics by: i) two-sided unpaired t-tests as indicated or compared to untreated cells ( b, c ), control-diet mice (d, g) , or to ML162-treated cells ( e )

In these cases one must infer that the G6PD() state is a selective disadvantage for hematopoietic stem cells

Tumor cell metabolism: cancers Achilles heel