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doi: 10.1165/ajrcmb.11.2.7519435 96 RanaldiG

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26 The trial began with single and multiple dose ascending stages in healthy volunteers and extended to elderly non-PD participants in June 2024 to control for age-related effects

Studies have shown that quercetin is a classic activator of the nuclear factor E2-related factor 2 (Nrf2) pathway and can significantly enhance the activity of intracellular antioxidant enzymes (such as superoxide dismutase and catalase) (Wang et al., 2017)

Glucose-lowering effects of orally administered superoxide dismutase in type 2 diabetic model rats