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In Phase 3 trials, about 25% of women on Vyleesi had a meaningful increase in their desire score (measured by a validated Female Sexual Function Index domain) compared to ~17% on placebo, and similarly saw a reduction in sexual distress

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[DOI] [PubMed] [Google Scholar] 956.Miettinen A.K., Heinonen P.K., Laippala P., Paavonen J

Recruited APCs are capable of LNP uptake and protein expression and can subsequently migrate to the local draining lymph nodes where T cell priming occurs (EMA, 2020a). Because of this inherent innate immune activity, it is not necessary to formulate the mRNA vaccines with additional adjuvants