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muscular, such as undernutrition, pre-diabetic or diabetic states, in hemodyalysis, hyperlipemia, heart disease and liver failure

After vascular endothelial dysfunction, the exposure of collagen and tissue factor triggers thrombus formation (Furie and Furie, 2008), while vascular calcification (VC) increases vessel rigidity and facilitates thrombosis (Lee et al., 2020)

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However, this pathway may lead to carnitine depletion which may be clinically problematic

Compliance of 130% was considered as non-compliant and any subject demonstrating non-compliance for two consecutive visits was withdrawn from the study