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Description

Type II DGK, which includes the delta, eta, and kappa isoforms, each contain an N-terminal pleckstrin homology (PH) domain that interacts with phosphatidylinositol, a C-terminal sterile -motif (SAM) domain, and two catalytic domains in addition to the two C1 domains

In its early phases of development, LM may display subtle features, with only mild cellular atypia and a mixed junctional and lentiginous appearance of proliferating melanocytes with occasional nests [6,7]

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Redox proteomics studies led to the identification of a large number of oxidatively modified proteins from brain tissue, biofluids, or other biological samples, potentially involved in the pathogenesis and/or progression of neurodegenerative diseases characterized by increased OS (29, 296)