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Abstract The cohesin complex mediates sister-chromatid cohesion by topologically entrapping DNA within an SMC1-SMC3-RAD21 ring, yet how Sororin preserves cohesion beyond its known role of antagonizing Pds5 binding to the release factor Wapl has remained unclear
Promoter hypermethylation of tumor suppressor genes, such as TP53 , CDKN2A , and MLH1 , leads to transcriptional silencing, contributing to leukemogenesis and resistance to apoptosis
Harmon et al
Overall, following the levofloxacin treatment, the patient was repeatedly hospitalised in neurological and orthopaedic wards over a period of 3 years
Analgesic intake and the risk of upper gastrointestinal bleeding
